Lota started his professional career with Zanaco FC of Zambia in 1989 before leaving for Nchanga Rangers at the beginning of the 1991 season.
At Nchanga Rangers he established a midfield partnership with Abeauty Kunda but later left Nchanga to join Kabwe Warriors after a failed attempt to rejoin Zanaco.
He never settled and left after one season to join Konkola Blades.
It was at Konkala where the late brother to Kalusha Bwalya, Benjamin transformed Lota from a midfielder to a lethal striker who went on to win the golden boot in 1995 and later became a strong target for international clubs.
A contractual conflict later emerged between FC Sion and Dangerous Aces with each team claiming to be the rightful owner of the player.
He was part of the Zambian African Nations Cup teams in 1996, 1998, 2000 and 2002 He has two brothers who are also footballers, Charles Lota (younger) and Lawrence Lota (older). At the 2002 African Cup of Nations, Dennis played alongside Charles in the Zambian attack formation.
In March 2011, the football team Moroka Swallows had elevated Dennis Lota to the first team as one of the assistant coaches.
Lota died on 4 February 2014 in South Africa of suspected malaria